atopic dermatitis

Filaggrin degradation products may explain higher rate of dermatitis in the winterA decrease in the levels of natural moisturizing factors and an increase in the density of corneocytes may explain why dermatitis and xerosis are worse in the winter.
Modest increase in risk of death with ADResearchers suggest that an assessment of cardiovascular risk factors in the atopic dermatitis patient population is prudent.
Dupilumab controls atopic dermatitis symptoms in patients with asthmaAdults with moderate to severe atopic dermatitis with comorbid asthma experience the same improvement in disease signs and symptoms with dupilumab treatment as those without asthma, according to pooled data from two large phase three clinical trials.
The atopic march strides toward eosinophilic esophagitisEczema, food allergy, and asthma independently and cumulatively increase the risk for eosinophilic esophagitis (EoE), according to findings presented at the 2018 American Academy of Allergy, Asthma & Immunology and World Allergy Organization Joint Congress in Orlando.
Shift to short chain fatty acids in the skin may explain AD lesionsAlterations in lipid metabolism can be detrimental to skin barrier function leading to atopic dermatitis, researchers have found.
Gene identified as having a role in suppressing atopic dermatitisThe transcription factor "retinoid-related orphan receptor-alpha" (RORA) has been identified as a regulator of T regulatory (Treg) genes responsible for suppressing allergic skin inflammation, researchers report.
Switching biologic treatments in dermatologyNot all biologic treatments are equal. Side effects, effectiveness, cost and administration style are among factors physicians should consider when switching treatments, experts report at AAD 2018.
Atopic dermatitis: From guidelines to practiceThis week during the annual meeting of the American Academy of Dermatology in San Diego, Robert Sidbury, M.D., addressed developments in atopic dermatitis treatments since the publication of treatment guidelines in 2014.
The promise of biologic therapy in dermatologyDuring the American Academy of Dermatology’s annual meeting, physicians addressed the monumental changes that have occurred since the advent of biologic therapy for systemic autoimmune conditions, such as psoriasis and atopic dermatitis. Today, some patients are able to achieve complete disease clearance. Although there may be viable treatments for these conditions, access to care and medication adherence remain top issues, physicians say.
Moisturizing: False claims and problematic ingredients
Moisturizing: False claims and problematic ingredientsDermatologists recommend moisturizers for patients who suffer from atopic dermatitis, contact dermatitis and psoriasis. Some over-the-counter moisturizers contain allergens patients should avoid. For details, print our table-of-the-month.