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Biologic treatments for moderate-to-severe atopic dermatitis

Ocular comorbidities associated with atopic dermatitisOcular comorbidity risk is already high in patients with atopic dermatitis and may increase even further as biologic agents are introduced, a study shows.
Atopic dermatitis and psoriasis as a spectrum conditionThinking of psoriasis and atopic dermatitis as a spectrum, rather than separate diseases might lead to better understanding, and potentially better treatments.
Atopic Dermatitis in 2018Until recently, atopic dermatitis treatments were primarily limited to topical corticosteroids and systemic immunosuppressants. Now, two new therapies have reached clinical practice. Nineteen more are in development.
Dupilumab tames AD in difficult-to-treat patientsDupilumab given concomitantly with topical corticosteroids significantly improved signs and symptoms of atopic dermatitis (AD) in adults refractory to or intolerant of cyclosporine A, a study shows.
Recruitment underway for atopic dermatitis serlopitant trialEarly trial results show a significant reduction of itch with the oral NK-1 antagonist serlopitant
When other treatments fail in atopic dermatitis, dupilumab succeedsDupilumab plus topical corticosteroids safe and effective after failure of cyclosporine in moderate-to-severe atopic dermatitis
The factors that drive atopic dermatitisThere are two pathways that lead to atopic dermatitis. Their origins differ, but they both impair the immune system and skin barrier in AD.
Relief from the itch in atopic dermatitisAn experimental drug designed to control itching in people with moderate-to-severe AD shows promise in early trial.
Gene mutation identified in atopic dermatitisA new study shows that mutations in the gene CARD11 are associated with severe atopic disease.
House dust mites and severe atopic dermatitis: A new connectionPatients with severe atopic dermatitis who have lower serum vitamin D levels have a high sensitivity to house dust mites which can aggravate their condition, a new study shows.