Oncology

Melanoma and the wrong siteWrong-site surgeries are preventable. In this article, Dr. Goldberg outlines a few measures.
FDA expands ipilimumab approval to pediatric melanomaThe US Food and Drug Administration (FDA) has expanded the approval of ipilimumab (Yervoy) to include the treatment of pediatric melanoma patients 12 years and older with unresectable or metastatic disease.
New pathways to cancer therapyA novel oral formulation of itraconazole (SUBA-Itraconazole, HedgePath Pharmaceuticals) is providing dramatic benefit for patients with basal cell carcinoma nevus syndrome (BCCNS, also known as Gorlin syndrome) and with a favorable safety profile, according to a recent interim analysis of data collected in a phase IIb study.
Skin cancer screeningData-driven screening guidelines for skin cancer have been published electronically, in reaction to the U.S. Preventive Services Task Force’s 2016 draft recommendation statement on skin cancer screening.
ECP may prevent mycosis fungoides progressionExtracorporeal photopheresis is underused for early-stage mycosis fungoides. ECP is capable of correcting the cytokine imbalance seen in patients with MF and results in an increase of Th1 cytokines. Clinicians should consider more frequent use in select patients
Lasers in melanoma careLaser for melanoma in situ (MIS) should generally be reserved for nonsurgical, usually elderly patients. When indicated, MIS may be treated with CO2 laser or with combined Q-switched Nd:YAG and imiquimod. Any atypical-appearing lesion should be biopsied prior to the start of a laser treatment.
Skin cancer quick reference
Skin cancer quick referenceThe May Table of the Month goes over tips for properly diagnosing skin cancer types.
Skin cancer advancesGenetic profiling is valuable in both diagnosis and prognosis of skin cancer. Hedgehog inhibitors and (superficial radiation therapy) SRT are strong contenders for treating nonmelanoma skin cancer. Advances in targeted therapies and biologics are part of the new wave of melanoma treatments.
Derm sounds alarm about Hispanics and skin cancerDermatologists should be versed and informed about the specific attitudes and lifestyle habits that could be fueling rising skin cancer risk in the Hispanic population, according to dermatologist Maritza I. Perez, M.D.
Psoriasis and skin cancerCyclosporine and PUVA clearly increase the risk of squamous cell carcinomas, and there is evidence that TNF blockers and methotrexate may do so to a lesser degree. UVB phototherapy has not been shown to cause skin cancer. Acitretin offers protection against the development of basal cell and squamous cell carcinomas.

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