Keloid disorder: a clinical management update
New treatments options offer hope to patients
Cryotherapy and intralesional injections of the chemotherapy drug vincristine can be effective treatments for keloids, according to a presentation at the lst International Keloid Symposium recently held in New York.
“For over 100 years now, the biggest issue we have had in treating keloid disorder and trying to help patients with keloid lesions on their skin has been lack of scientific data and evidence-based medicine. Hence, every physician, no matter the location of his practice, uses whatever method he believes will help,” says Michael H. Tirgan, M.D., a medical oncologist in private practice in New York City. Dr. Tirgan founded the Keloid Research Foundation in 2011.
Treating keloids with a combination of surgery and radiation dates back to the early 1900s, according to Dr. Tirgan, whereas steroid injections have been the only medicine used in the past 50 years.
Dr. Tirgan and others are trying to change the paradigm for keloid therapy.
“Even as of 2016, we do not know the proper dosage of radiation therapy or steroids,” Dr. Tirgan tells Dermatology Times in a post-symposium interview. “We also constantly see patients who have been treated by a combination of surgery/radiation/injections, but with failed results, and with keloid lesions that are larger than (they were) prior to receiving surgery or a combination of surgery and radiation therapy.”
“We recognize that a lot of these patients with large keloids have had surgery in the past,” Dr. Tirgan says.