Actinic keratoses have intermittent expression - - DermatologyTimes

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Dermatology Times
Actinic keratoses have intermittent expression


Dermatology Times E-News

Montreal — Actinic keratoses (AKs) present with intermittent expression, even in patients with extensive damage, according to an 11-month study presented at the recent Society for Investigative Dermatology meeting.

Researchers at the University of Alabama in Birmingham followed the natural course of AKs in 26 individuals with extensive actinic damage. At baseline, study participants had between 10 and 40 lesions, and at least one prior histological diagnosis of an AK or nonmelanoma skin cancer, according to MedPage Today.

Lesion mapping was done at baseline, three, six, nine and 11 months, and lesions were also biopsied at baseline and study end. At baseline, a total of 610 AKs were present in the study group, and the number was not significantly different at the end of the study, despite the development of 973 new lesions over the study period, MedPage reports.

About 40 percent of lesions present at baseline had regressed by month 11, and almost 200 of the lesions present at baseline regressed and then recurred, according to researchers.

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Source: Dermatology Times E-News,
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