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    Vaccine has potential to prevent genital herpes


    The new vaccine also appears to be safe. The researchers calculated the number of viruses needed to kill mice, then administered 1,000 times that number of delta-g D-2 viruses to mice that lacked immune systems. The result: The mice survived and didn’t develop herpes.

    “For the first time in history, we have successfully developed a vaccine that prevents HSV-1 and HSV-2, using an approach that experts thought was doomed to fail,” Dr. Jacobs says. “If this vaccine protects humans as it does mice, herpes could be eradicated.”

    The Einstein team plans to begin clinical trials on humans within a few years.

    “We hope that this vaccine candidate, which elicits a different type of immune response than prior vaccines, will prove equally protective in clinical studies,” Dr. Herold tells Dermatology Times. “We are planning to conduct the pre-clinical studies required by the Food and Drug Administration to allow us to move this vaccine into a Phase I clinical trial.”

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