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Drug-resistant disease re-emerge, gain strength


National report — Key concerns regarding infectious diseases with cutaneous manifestations include the strongyloidiasis parasite infection imageThis patient with strongyloidiasis, presented with dermatologic symptoms including a creeping eruption. (Photo: CDC)expanding reach of infections formerly thought rare and exotic, experts say. Meanwhile, they add, some infections rarely seen stateside in recent years are resurging.

Expanding global travel fuels the spread of many of these diseases, say Stephen K. Tyring, M.D., Ph.D., M.B.A., and Casey Carlos, M.D., Ph.D. Dr. Tyring is clinical professor of dermatology, microbiology/molecular genetics and internal medicine at the University of Texas Health Science Center, and medical director of the Center for Clinical Studies in Houston. Dr. Carlos is assistant professor of internal medicine in the division of dermatology, University of California, San Diego.


FDA suggests approval of two antibiotics for skin infections

Going viral

Dr. Tyring also blames complacency. With fewer parents getting their children vaccinated for measles, for example, he says that 2013 saw more measles cases in the United States (175 as of Dec. 6) than any prior year of the 21st century.

Accordingly, he says, “Infectious diseases of the 20th century such as measles are not eradicated. And some diseases that were very rare in the United States at the beginning of the 21st century are coming back with a vengeance.” Therefore, he says that for every disease for which there is a vaccine, “It’s important that people get vaccinated.”

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Purpura, whether after trauma or an aesthetic procedure, is undesirable to patients. The ecchymoses can last for up to two weeks, and dyspigmentation can persist even longer.

The commercialization of ingenol mebutate (Picato, LEO Pharma) a medication that is currently approved in the United States and many other countries for the treatment of actinic keratosis, is an example of how enthusiasm and commitment can drive innovation, a LEO Pharma general manager says.