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    Alternative therapies hold promise for rosacea

    Oral and topical options have positive outcomes

    Papules, pustules, and erythema are the hallmarks of rosacea, the chronic inflammatory skin disorder that generally involves the central face. Rosacea typically affects adults in the third decade and has a predilection for those with fair skin, blue eyes, and Celtic heritage.1

    Peter Lio, M.D.Dr. Lio, Medical Dermatology Associates of Chicago While the underlying pathophysiologic details remain obscure, recent studies suggest that rosacea is initiated by inappropriate innate immune responses to environmental stimuli which then lead to inflammation, skin barrier dysfunction, and vascular abnormalities.2

    What is clear is that patients are often very troubled by rosacea.

    Conventional therapies are generally effective, yet few adequately treat the erythema or flushing component.3 Some patients also dislike the notion of being on oral antibiotic therapy, even low-dose sub-antimicrobial preparations. In concert, these perhaps fuel the desire for alternatives, some of which hold promise, as we shall see.

    Next: Nicotinamide

    Peter Lio, M.D.
    Peter Lio, M.D., is assistant professor of clinical dermatology and pediatrics at Northwestern University’s Feinberg School of Medicine, ...

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