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    3-D imaging tracks port wine stain changes



    A new study shows that three-dimensional high precision surface imaging can be used to monitor changes in the area and volume of port wine stains following laser treatment.

    A research team led by Alice Frigerio, M.D., Ph.D., of Harvard Medical School, Boston, conducted a retrospective review involving 55 patients with 59 port wine stains treated over a 20-month time period. 3-D surface imaging photogrammetric software was used to measure the area and volume of the lesions before and after a series of sequential pulsed dye laser and/or alexandrite laser treatments.

    The researchers found that the initial average measured area was 44.3 cm², which decreased significantly to a final average measured area of 36.9 cm². For all port wine stains, the average volume change was 1.20 cc, while for lesions that received five or more laser treatments within the 20-month study period, the average volume change was 1.90 cc.

    “We reported a new method to objectively track the change in volume and area of port-wine stains following laser treatments,” Dr. Frigerio tells Dermatology Times. “Future improvement of the software will eventually allow area calculation based on a color-match analysis, eliminating any experimental bias and further increasing the accuracy of the system in detecting color change.”

    The authors wrote that more research is needed to determine if statistically significant changes correlate with clinically appreciable changes.

    The study was published online Oct. 24 in Lasers in Surgery and Medicine.


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