Michael G Burke, MD
Coronary artery lesions in Kawasaki disease are related to gene polymorphisms
The risk of coronary artery lesions (CALs) in Kawasaki disease (KD) is related to CYP2E1 gene polymorphisms, a study from Taiwan confirmed.
Study validates new test for bacterial vs viral infections
A novel assay for distinguishing bacterial from viral infections significantly outperformed routine laboratory parameters and biomarkers in a study using serum remnants from children suspected to have acute infection.
Immediate amoxicillin is the most cost-effective choice for AOM
Using a cost-utility model of a hypothetical group of symptomatic children aged younger than 2 years who were diagnosed with acute otitis media (AOM), investigators evaluated whether antimicrobial therapy reduces time to symptom resolution, overall symptom burden, and persistence of infection.
M pneumoniae infection hits preschoolers hard
A study of Mycoplasma pneumoniae disease during an epidemic in Norway found that preschool children infected with this bacterium had a significantly higher risk of severe disease, particularly severe pneumonia, than school-aged children.
An app for assessing neonatal jaundice? You bet!
A study of the accuracy of a technology for assessing jaundice in outpatient neonates based on analysis of digital images demonstrated that this smartphone application (app) may be useful for screening newborns for jaundice.
Hospitalized preterm infants benefit from mothers’ recorded voices
Being exposed to recordings of their mothers’ voices limited pain preterm infants experienced while undergoing heel lance procedures, according to a study conducted in an Italian neonatal intensive care unit.
Half of children with reported penicillin allergy symptoms are not truly allergic
Parents of children who visit a pediatric emergency department often report that their child has an allergy to penicillin, which can lead to treatment with a less than optimal antibiotic.
Loss of a father is associated with impaired cellular function
The link between a child’s losing a father and poor health is well documented. Now a new study shines a light on the biologic factors that may underlie this association.
Pediatricians could do more to provide tobacco counseling
Most pediatricians advise patients and their parents who smoke to quit, and the proportion of those who do so changed little from 2004 to 2010, according to surveys conducted in those years.
Nonoperative management of acute appendicitis
Compared with traditional appendectomy, nonoperative management (NOM) of uncomplicated appendicitis using parenteral antibiotics is associated with more subsequent emergency department (ED) visits and hospitalizations, as well as more subsequent appendectomies.

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