In patients with sickle cell disease, therapy with crizanlizumab, an antibody against the adhesion molecule P-selectin, resulted in a significantly lower rate of sickle cell-related pain crises than placebo, a trial in 198 patients aged from 16 to 65 years showed.
Sales associates at health food stores, which primarily sell dietary supplements, often recommend creatine products and, sometimes, testosterone boosters to young teenaged boys, according to a study involving 244 stores in 49 states.
Women in the third trimester of pregnancy who take supplements of n-3 long-chain polyunsaturated fatty acids (LCPUFAs) reduce their children’s risk of persistent wheeze or asthma as well as of lower respiratory tract infections, a study in Denmark demonstrated.
In a study of almost 48,900 vaccinated individuals, investigators observed a temporal association between development of Bell’s palsy and administration of quadrivalent meningococcal conjugate vaccine (MCV4) that protects against serogroups A,C, Y, and W (MenACWY) when the vaccine was given at the same time as other vaccines.
Stepwise introduction of egg (starting with a low dose, which is then increased), along with aggressive treatment of atopic dermatitis (AD), is a safe and effective way to prevent hen’s egg allergy in high-risk infants, a study in Japan showed.
An interview-based study conducted in 372 parents visiting pediatric emergency departments with children aged younger than 4 years found that parents who used physical discipline were 2.8 times more likely than parents who did not use this form of discipline to report that their children engage in hitting, kicking, and throwing.
A large retrospective study of how infants with fever without a cause are evaluated found that physicians are selective in deciding which of these babies will have blood, urine, or cerebral spinal fluid cultures.
Results of a survey of more than 1360 parents conducted in pediatricians’ waiting rooms found that 75% of parents agree that pediatricians should advise about safe storage of firearms; those who disagreed were likely to be firearm owners.